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Filtered Search Results
eMolecules 288154-18-7 | tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Ambeed | MFCD04114477 | 243.307 | C11H21N3O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 1g | 552739296
tert-Butyl 4-amino-4-carbamoylpiperidine-1-carboxylate | Ambeed | 288154-18-7 | MFCD04114477 | 243.307 | C11H21N3O3 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)(CC1)C(N)=O | 1g | 552739296
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eMolecules 74124-79-1 | N,N'-Disuccinimidyl carbonate | Chem-Impex | MFCD00009767 | 256.170 | C9H8N2O7 | 99.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 25g | 112443062
N,N'-Disuccinimidyl carbonate | Chem-Impex | 74124-79-1 | MFCD00009767 | 256.170 | C9H8N2O7 | 99.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 25g | 112443062
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Aobchem 2-Fluoro-3-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 1704074-05-4 | C11H13BFNO4 | 500mg
2-Fluoro-3-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 1704074-05-4 | C11H13BFNO4 | 500mg
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Aobchem 2-Methoxy-8-quinolinecarboxaldehyde | ≥95% | CAS 885687-67-2 | C11H9NO2 | 1g
2-Methoxy-8-quinolinecarboxaldehyde | ≥95% | CAS 885687-67-2 | C11H9NO2 | 1g
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Aobchem 2-Methoxy-8-quinolinecarboxaldehyde | ≥95% | CAS 885687-67-2 | C11H9NO2 | 250mg
2-Methoxy-8-quinolinecarboxaldehyde | ≥95% | CAS 885687-67-2 | C11H9NO2 | 250mg
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Apexbio Technology LLC TAME 901-47-3 200mg
TAME (CAS 901-47-3) or Tosyl-L-arginine methyl ester is a small molecule inhibitor of the anaphase promoting complex/cyclosome (APC/C) a multisubunit ubiquitin ligase essential for mitotic progression TAME binds competitively to the APC/C interfering with the association of its coactivator Cdc20 and thereby suppressing APC/C-dependent ubiquitination and subsequent proteasomal degradation of key substrates such as cyclin B1 In Xenopus egg extracts TAME exhibits an IC50 of 12 M for APC/C inhibition This compound is widely employed in cell cycle research to investigate mitotic regulation APC/C function and ubiquitin-mediated proteolysis
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Medchemexpress LLC (R)-Baclofen (Arbaclofen) | 69308-37-8 | 99.50% | 213.66 | 200 MG
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R-Baclofen (Arbaclofen) is a selective GABAB receptor agonist commonly used in research. It exhibits agonist activity at human GABA-B B1/B2 receptors expressed in HEK293 cells, as assessed by the inhibition of forskolin-stimulated cAMP accumulation. In vivo studies demonstrate its ability to suppress audiogenic seizures in Fmr1-knockout mice and significantly reduce seizure incidence with acute administration.
- Selective GABAB receptor agonist.
- Exhibits agonist activity at human GABA-B B1/B2 receptors.
- Suppresses audiogenic seizures in Fmr1-knockout mice.
- Reduces seizure incidence in mice.
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Medchemexpress LLC Veliparib | 912444-00-9 | MFCD16661059 | 244.29 g/mol | C13H16N4O | 200 MG
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Veliparib (ABT-888) is a small-molecule inhibitor of poly(ADP-ribose) polymerases used in research to probe DNA repair pathways and for chemosensitization studies. It is supplied as a solid for analytical and preclinical research and has documented storage recommendations for powder and solutions.
- Potent PARP1 and PARP2 inhibition (Ki 5.2 nM and 2.9 nM).
- Molecular formula C13H16N4O and molecular weight 244.29 g/mol.
- Identified by CAS number 912444-00-9.
- Supplied as a powder with recommended storage: -20°C (3 years) or 4°C (2 years).
- Stable in solvent when stored at -80°C (1 year) or -20°C (6 months).
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Medchemexpress LLC Acotiamide monohydrochloride trihydrate | 773092-05-0 | 99.8% | 1 G
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Acotiamide monohydrochloride trihydrate is an orally active, selective, and reversible acetylcholinesterase (AChE) inhibitor with an IC50 of 1.79 μM. It can enhance gastric contractility and accelerate delayed gastric emptying. It has potential for research into functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory conditions.
- Orally active, selective, and reversible acetylcholinesterase (AChE) inhibitor
- Enhances gastric contractility and accelerates delayed gastric emptying
- Potential for research of functional dyspepsia and intestinal inflammatory conditions
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Medchemexpress LLC CLIP (86-100) | 648881-58-7 | 98.5% | 1674.10 | 1 MG
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CLIP (86-100) is a fragment consisting of amino acids 86 to 100 of the class II-associated invariant chain peptide (CLIP). This small self-peptide is a cleavage product of the invariant chain and resides in the HLA-II antigen binding groove, playing a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site.
- Consists of amino acids 86 to 100 of the class II-associated invariant chain peptide
- Plays a critical role in the assembly and transport of MHC class II alphabetaIi complexes
- Purity of 98.49%
- Molecular weight: 1674.10
- White to off-white solid appearance
- Soluble in H2O at ≥ 100 mg/mL
- Store as powder at -80°C for 2 years or -20°C for 1 year
- Store in solvent at -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC Oridonin | 28957-04-2 | 99.9% | 364.43 | 200 MG
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Oridonin is a diterpenoid isolated from *Rabdosia rubescens*. It acts as an inhibitor of AKT, with IC50s of 8.4 μM for AKT1 and 8.9 μM for AKT2. Oridonin also exhibits anti-tumor, anti-bacterial, and anti-inflammatory effects. It is intended for research use only.
- Inhibits AKT1 (IC50: 8.4 μM) and AKT2 (IC50: 8.9 μM)
- Exhibits anti-tumor effects
- Exhibits anti-bacterial effects
- Exhibits anti-inflammatory effects
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Apexbio Technology LLC GSK1070916 942918-07-2 200mg
GSK1070916 (CAS 942918-07-2) is a selective ATP-competitive inhibitor targeting Aurora kinase B and C displaying Ki values of 0 38 nM and 1 5 nM respectively The compound demonstrates marked selectivity over Aurora kinase A with IC50 values of approximately 5 nM (Aurora B) versus 1259 nM (Aurora A) In vitro studies show that GSK1070916 inhibits proliferation of human lung cancer cells (A549) with an EC50 of roughly 7 nM Additionally the compound effectively reduces phosphorylation of histone H3 an Aurora B substrate and exhibits tumor growth inhibition in HL-60 xenograft mouse models GSK1070916 is utilized in tumor biology research investigating Aurora kinase signaling pathways
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Medchemexpress LLC Lificiguat | 170632-47-0 | 99.7% | 304.34 | 200 MG
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Lificiguat (YC-1) is a soluble guanylyl cyclase (sGC) activator that binds to the β subunit of sGC. It stimulates sGC activity, especially in the presence of CO or NO, leading to several hundred-fold activation. This compound has also been shown to inhibit tumor growth and improve rodent learning behavior.
- Binds to the β subunit of soluble guanylyl cyclase (sGC)
- Activates sGC, synergistically with carbon monoxide or nitric oxide
- Inhibits tumor growth
- Improves rodent learning behavior
- Enhances long-term potentiation (LTP)
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Aobchem 3-Chloro-5-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 957120-55-7 | C11H13BClNO4 | 5g
3-Chloro-5-(morpholine-4-carbonyl)phenylboronic acid | ≥97% | CAS 957120-55-7 | C11H13BClNO4 | 5g
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Medchemexpress LLC Floxuridine | 50-91-9 | 99.97% | C9H11FN2O5 | 200 MG
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Floxuridine is a pyrimidine analog and an oncology antimetabolite. It inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating ATM and ATR checkpoint signaling pathways. Floxuridine is a potent inhibitor for S. aureus infection and induces cell apoptosis, in addition to having antiviral effects against HSV and CMV.
- Inhibits Poly(ADP-Ribose) polymerase
- Induces DNA damage by activating ATM and ATR checkpoint signaling pathways
- Acts as a potent inhibitor for S. aureus infection
- Induces cell apoptosis
- Shows antiviral effects against HSV and CMV
- Potentiates the sensitivity of ovarian cancer cells when co-exposed with PARP inhibitors
- Causes G1/S-phase arrest in ovarian cancer cells
- Reduces the virulence of Staphylococcus aureus
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